2016 AHA Statin Drug Interactions Q2

2016 AHA Statin Drug Interactions

According to the 2016 AHA Scientific Statement:
“Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease” p e477

” …¬†the combination of ________ with lovastatin, pravastatin, and simvastatin is potentially harmful and should be avoided …”

a) amiodarone
b) amlodipine
c) fenofibrate/fenofibric acid
d) gemfibrozil

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(D)

” … the combination
of gemfibrozil with lovastatin, pravastatin, and
simvastatin is potentially harmful and should be avoided.
Although gemfibrozil interacts with atorvastatin,
pitavastatin, and rosuvastatin, the result is only a minor
increase in statin concentrations, and the combination
may be considered if clinically indicated. Fluvastatin may
be used in combination with gemfibrozil without any specific
dose limitations, …”

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